2CBecca

2CBecca
Clinical data
Drug class	Serotonin receptor modulator
ATC code	None;
Identifiers
	IUPAC name 4-(4-bromo-2,5-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C17H18BrNO2
Molar mass	348.240 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1cc(Br)c(cc1C1CNCc2c1cccc2)OC;
	InChI InChI=1S/C17H18BrNO2/c1-20-16-8-15(18)17(21-2)7-13(16)14-10-19-9-11-5-3-4-6-12(11)14/h3-8,14,19H,9-10H2,1-2H3; Key:LRHOKFHXSNZVLA-UHFFFAOYSA-N;

2CBecca, also known as 4-(4-bromo-2,5-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline, is a serotonin receptor modulator of the phenethylamine, 2C, and N-benzylphenethylamine families.^[1]^[2] It is a cyclized phenethylamine analogue of the serotonergic psychedelic 25B-NBOMe in which the N-benzyl ethyl amine side chain has been cyclized to form a tetrahydroisoquinoline ring.^[1]^[2] The drug shows affinity for the serotonin 5-HT_2A and 5-HT_2C receptors (K_i = 39–71 nM and 267–850 nM, respectively).^[1]^[2]^[3]^[4] 2CBecca was first described in the scientific literature by Michael Robert Braden of the lab of David E. Nichols at Purdue University in 2007.^[2]

References

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