6-EAPB

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6-EAPB
File:6-EAPB structure.svg
Legal status
Legal status
Identifiers
  • 1-(benzofuran-6-yl)-N-ethylpropan-2-amine
CAS Number
ChemSpider
UNII
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC13H17NO
Molar mass203.285 g·mol−1
3D model (JSmol)
  • CCNC(CC1=CC2=C(C=CO2)C=C1)C
  • InChI=1S/C13H17NO.ClH/c1-3-14-10(2)8-11-4-5-12-6-7-15-13(12)9-11;/h4-7,9-10,14H,3,8H2,1-2H3;1H
  • Key:MUFUSNCKTVRMLR-UHFFFAOYSA-N

6-EAPB, also known as 1-(benzofuran-6-yl)-N-ethylpropan-2-amine, is a potentially psychedelic and potentially entactogenic drug of the benzofuran class;[1] it is structurally related to 6-APB and MDMA.

Pharmacology

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Pharmacodynamics

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6-EAPB is a potent monoamine reuptake inhibitor.[2] It shows very low potency as a serotonin 5-HT2A receptor agonist.[2]

Society and culture

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As an N-ethyl derivative of 6-APB, 6-EAPB fell outside the scope of the Temporary Class Drug ban issued by the Home Office on June 10, 2013.[3] The ACMD has advised that 6-EAPB (and other benzofurans) are moved to Class B,[4] this came into action on 10 June 2014.[5]

See also

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References

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  2. ^ a b Stalberga, D., Kronstrand, R., Schranz, B., van Zijl, N., Karlman, S., Aref, S., ... & Gréen, H. (2025). Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor. https://doi.org/10.22541/au.176253891.19158813/v1
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