SB-243213

SB-243213
Identifiers
	IUPAC name 5-methyl-N-(6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl)-6-(trifluoromethyl)indoline-1-carboxamide;
CAS Number	200940-23-4;
PubChem CID	443391;
ChemSpider	391620;
UNII	PA86JD65ZJ;
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).;
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C22H19F3N4O2
Molar mass	428.415 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=C(C(F)(F)F)C=C(N(C(NC2=CN=C(OC3=C(C)N=CC=C3)C=C2)=O)CC4)C4=C1;
	InChI InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30); Key:ZETBBVYSBABLHL-UHFFFAOYSA-N;

SB-243213 is a research chemical which acts as a selective inverse agonist for the 5HT_2C receptor and has anxiolytic effects. It has better than 100x selectivity for 5-HT_2C over all other receptor subtypes tested, and a longer duration of action compared to older 5-HT_2C antagonist ligands.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

References

^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

Stub icon

This article about an anxiolytic is a stub. You can help Wikipedia by expanding it.

[1] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[2] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[3] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[4] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[5] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[6] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[7] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[8] Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

SB-243213

See also

References

Navigation menu

Identifiers

IUPAC name 5-methyl-N-(6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl)-6-(trifluoromethyl)indoline-1-carboxamide
CAS Number	200940-23-4
PubChem CID	443391
ChemSpider	391620
UNII	PA86JD65ZJ
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₂H₁₉F₃N₄O₂
Molar mass	428.415 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=C(C(F)(F)F)C=C(N(C(NC2=CN=C(OC3=C(C)N=CC=C3)C=C2)=O)CC4)C4=C1
InChI InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30) Key:ZETBBVYSBABLHL-UHFFFAOYSA-N

SB-243213

See also

References

Navigation menu

Search