Metanephrine

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Metanephrine
File:3-Methoxyadrenalin Structural Formulae V.1.svg
Names
IUPAC name
4-(1-hydroxy-2-methylamino-ethyl)-2-methoxy-phenol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
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MeSH Metanephrine
UNII
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  • InChI=1S/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3 checkY
    Key: JWJCTZKFYGDABJ-UHFFFAOYSA-N checkY
  • InChI=1/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3
    Key: JWJCTZKFYGDABJ-UHFFFAOYAB
  • Oc1ccc(cc1OC)C(O)CNC
Properties
C10H15NO3
Molar mass 197.231 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Metanephrine, also known as metadrenaline, is a metabolite of epinephrine (also known as adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association, 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm.[1]

References

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  1. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value). Free full text with registration