TRPS1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Zinc finger transcription factor Trps1 is a protein that in humans is encoded by the TRPS1 gene.[1][2][3]
This gene encodes a GATA-like transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho–rhino–phalangeal syndrome (TRPS) types I–III (also known as the Langer–Giedion syndrome).[4]
References
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Further reading
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External links
[edit | edit source]- TRPS1 protein, human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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