LMX1B
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LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene.[1][2]
Function
[edit | edit source]LMX1B is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb.[3]
Clinical significance
[edit | edit source]Loss-of-function mutations in the LMX1B gene are associated with Nail-patella syndrome.[4]
References
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Further reading
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External links
[edit | edit source]- GeneReviews/NIH/NCBI/UW entry on Nail-Patella Syndrome
- LIM+homeobox+transcription+factor+1+beta at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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