PBX2
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene.[1][2]
Function
[edit | edit source]This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.[2]
Interactions
[edit | edit source]PBX2 has been shown to interact with HOXA9.[3]
References
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Further reading
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External links
[edit | edit source]- PBX2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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