FOSL1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene.[1][2]
Function
[edit | edit source]The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.[2]
Interactions
[edit | edit source]FOSL1 has been shown to interact with USF1 (human gene)[3] and C-jun.[3]
See also
[edit | edit source]References
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Further reading
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External links
[edit | edit source]- FOSL1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- FactorBook FOSL1
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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