Tandamine

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Tandamine
Clinical data
ATC code
  • none
Identifiers
  • 2-(9-ethyl-1-methyl-3,4-dihydrothiopyrano[3,4-b]indol-1-yl)-N,N-dimethylethanamine
CAS Number
PubChem CID
ChemSpider
UNII
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC18H26N2S
Molar mass302.48 g·mol−1
3D model (JSmol)
  • CCn3c1ccccc1c2CCSC(C)(CCN(C)C)c23
  • InChI=1S/C18H26N2S/c1-5-20-16-9-7-6-8-14(16)15-10-13-21-18(2,17(15)20)11-12-19(3)4/h6-9H,5,10-13H2,1-4H3
  • Key:BRPOADLGOFPKKJ-UHFFFAOYSA-N
  (verify)

Tandamine is a selective norepinephrine reuptake inhibitor with a tricyclic structure.[1][2][3] It was developed in the 1970s as an antidepressant but was never commercialized.[1][2][3] Tandamine is analogous to pirandamine, which, instead, acts as a selective serotonin reuptake inhibitor (SSRI).[4][5]

The exact identical same structure, although this time changing the thioether to a methylene group revealed a strongest compound of the series called AY 24614.[6]

See also

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References

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