Iproclozide

Iproclozide
	File:Iproclozide.svg
Clinical data
Routes of; administration	Oral
ATC code	N06AF06 (WHO) ;
Legal status
Legal status	BR: Class C1 (Other controlled substances); In general: uncontrolled;
Identifiers
	IUPAC name 2-(4-chlorophenoxy)-N-isopropyl-acetohydrazide;
CAS Number	3544-35-2 check;
PubChem CID	19063;
ChemSpider	17998 check;
UNII	1II9D6CB3J;
KEGG	D07338 check;
ChEMBL	ChEMBL91238 check;
E number	{{#property:P628}}
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ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C11H15ClN2O2
Molar mass	242.70 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc1ccc(OCC(=O)NNC(C)C)cc1;
	InChI InChI=1S/C11H15ClN2O2/c1-8(2)13-14-11(15)7-16-10-5-3-9(12)4-6-10/h3-6,8,13H,7H2,1-2H3,(H,14,15) check; Key:GGECDTUJZOXAAR-UHFFFAOYSA-N check;
	(verify)

Iproclozide (trade names Sursum, Sinderesin) is an irreversible and selective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant, but has since been discontinued.^[2] It has been known to cause fulminant hepatitis and there have been at least three reported fatalities due to administration of the drug.^[3]^[4]

References

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[2]

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[4]

v t e Anxiolytics (N05B)
5-HT_1ARTooltip 5-HT1A receptor agonists	Buspirone Gepirone Tandospirone
GABA_ARTooltip GABAA receptor PAMsTooltip positive allosteric modulators	Benzodiazepines: Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam^# Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam^# Medazepam Nordazepam Oxazepam Pinazepam Prazepam; Others: Alpidem^‡ Barbiturates (e.g., phenobarbital) Carbamates (e.g., meprobamate) Carisoprodol Chlormezanone^‡ Ethanol (alcohol) Etifoxine
Gabapentinoids (α₂δ VDCC blockers)	Gabapentin Gabapentin enacarbil Phenibut Pregabalin
Antidepressants	SSRIsTooltip Selective serotonin reuptake inhibitors (e.g., escitalopram) SNRIsTooltip Serotonin-norepinephrine reuptake inhibitors (e.g., duloxetine) SARIsTooltip Serotonin antagonist and reuptake inhibitors (e.g., trazodone) TCAsTooltip Tricyclic antidepressants (e.g., clomipramine^#) TeCAsTooltip Tetracyclic antidepressants (e.g., mirtazapine) MAOIsTooltip Monoamine oxidase inhibitors (e.g., phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine
Sympatholytics (Antiadrenergics)	Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists (e.g., clonidine, dexmedetomidine, guanfacine) Beta blockers (e.g., propranolol, atenolol, betaxolol, nadolol, oxprenolol, pindolol)
Others	Benzoctamine Cycloserine Fabomotizole Hydroxyzine Lorpiprazole Mebicar Mepiprazole Nicotine (tobacco) Opipramol Oxaflozane^‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Iproclozide

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Clinical data
File:Iproclozide.svg
Routes of administration	Oral
ATC code	N06AF06 (WHO)
Legal status
Legal status	BR: Class C1 (Other controlled substances)^[1] In general: uncontrolled
Identifiers
IUPAC name 2-(4-chlorophenoxy)-N-isopropyl-acetohydrazide
CAS Number	3544-35-2^checkY
PubChem CID	19063
ChemSpider	17998^checkY
UNII	1II9D6CB3J
KEGG	D07338^checkY
ChEMBL	ChEMBL91238^checkY
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₁H₁₅ClN₂O₂
Molar mass	242.70 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc1ccc(OCC(=O)NNC(C)C)cc1
InChI InChI=1S/C11H15ClN2O2/c1-8(2)13-14-11(15)7-16-10-5-3-9(12)4-6-10/h3-6,8,13H,7H2,1-2H3,(H,14,15)^checkY Key:GGECDTUJZOXAAR-UHFFFAOYSA-N^checkY
(verify)

Iproclozide

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References

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