Ethinylestradiol/norethisterone

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Not to be confused with Ethinylestradiol/norethisterone acetate.

Ethinylestradiol/norethisterone
Combination of
EthinylestradiolEstrogen
NorethisteroneProgestogen
Clinical data
Trade namesAlyacen, Aranelle, Balziva, others
Other namesEE/NET
AHFS/Drugs.comMonograph
MedlinePlusa601050
License data
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
  • None
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Ethinylestradiol/norethisterone (EE/NET), or ethinylestradiol/norethindrone, is a combination birth control pill which contains ethinylestradiol (EE), an estrogen and norethisterone (NET), a progestin.[1] It is used for birth control, symptoms of menstruation, endometriosis, and menopausal symptoms.[1][2] Other uses include acne.[1] It is taken by mouth.[1] Some preparations of EE/NET additionally contain an iron supplement in the form of ferrous fumarate.[3]

Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems.[2] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots.[2][4] It, however, may be started immediately after a miscarriage or abortion.[4] Smoking while using combined birth control pills is not recommended.[5] It works by stopping ovulation, making the uterus not suitable for implantation, and making the mucus at the opening to the cervix thick.[4]

This combination pill was approved for medical use in the United States in 1964.[6] It is on the World Health Organization's List of Essential Medicines.[7] It is available as a generic medication.[8] It is marketed under a large number of brand names.[9] In 2023, the combination of ethinylestradiol with norethisterone or with norethisterone acetate was the 79th most commonly prescribed medication in the United States, with more than 8 million prescriptions.[10][11]

See also

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References

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