Estrobin

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Estrobin
File:Estrobin.svg
Clinical data
ATC code
  • None
Identifiers
  • 1,1'-(2-Bromo-2-phenyl-1,1-ethenediyl)bis(4-ethoxybenzene)
CAS Number
PubChem CID
ChemSpider
UNII
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC24H23BrO2
Molar mass423.350 g·mol−1

Estrobin, also known as α,α-di(p-ethoxyphenyl)-β-phenylbromoethylene and commonly abbreviated as DBE, is a synthetic, nonsteroidal estrogen of the triphenylethylene group that was never marketed.[1][2] Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it.[1][2] Estrobin, similarly to other triphenylethylenes, is very lipophilic and hence very long-lasting in its duration of action.[1][2] Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body.[2]

See also

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References

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