Syringic acid

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Syringic acid
Chemical structure of syringic acid
Chemical structure of syringic acid
Names
Preferred IUPAC name
4-Hydroxy-3,5-dimethoxybenzoic acid
Other names
Gallic acid 3,5-dimethyl ether
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
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EC Number
  • 208-486-8
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KEGG
UNII
  • {{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
  • InChI=1S/C9H10O5/c1-13-6-3-5(9(11)12)4-7(14-2)8(6)10/h3-4,10H,1-2H3,(H,11,12)
    Key: JMSVCTWVEWCHDZ-UHFFFAOYSA-N
  • COC1=CC(=CC(=C1O)OC)C(=O)O
Properties
C9H10O5
Molar mass 198.174 g·mol−1
Melting point 206 to 209
Hazards
GHS labelling:[1]
GHS07: Exclamation mark
Warning
H315, H319, H335
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
File:Syringic acid UV visible spectrum.PNG
UV visible spectrum of syringic acid.

Syringic acid is a naturally occurring phenolic compound and dimethoxybenzene that is commonly found as a plant metabolite.

Natural occurrence

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Syringic acid can be found in several plants including Ardisia elliptica and Schumannianthus dichotomus.[1] It is biosynthesized by the shikimic acid pathway in plants.[2]

Synthesis

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Syringic acid can be prepared by selectively hydrolyzing (demethylating) eudesmic acid with 20% sulfuric acid.[3]

Presence in food

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Syringic acid can be found in several fruits including olives, dates, spices, pumpkin, grapes,[4] acai palm,[5] honey, red wine, among others.[2] Its presence in the ancient Egyptian drink shedeh could confirm it was made out of grape, as syringic acid is released by the breakdown of the compound malvidin, also found in red wine. It is also found in vinegar.[6]

Applications

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Various studies have found syringic acid to have potentially useful properties such as anti-oxidant, anti-microbial, anti-inflammation, anti-cancer, and anti-diabetic.[2]

Syringic acid can be enzymatically polymerized. Laccase and peroxidase induced the polymerization of syringic acid to give a poly(1,4-phenylene oxide) bearing a carboxylic acid at one end and a phenolic hydroxyl group at the other.[7]

See also

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References

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