Clogestone acetate

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Clogestone acetate
Clinical data
Other namesChlormadinol acetate; AY-11440; 3β,17α-Diacetoxy-6-chloropregna-4,6-diene-20-one
Drug classProgestogen; Progestogen ester
Identifiers
  • (1S,2R,5S,10R,11S,14R,15S)-14-acetyl-5-(acetyloxy)-8-chloro-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-6,8-dien-14-yl acetate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC25H33ClO5
Molar mass448.98 g·mol−1
3D model (JSmol)
  • CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(CCC34C)OC(=O)C)Cl)C)OC(=O)C
  • InChI=1S/C25H33ClO5/c1-14(27)25(31-16(3)29)11-8-20-18-13-22(26)21-12-17(30-15(2)28)6-9-23(21,4)19(18)7-10-24(20,25)5/h12-13,17-20H,6-11H2,1-5H3/t17-,18+,19-,20-,23+,24-,25-/m0/s1
  • Key:KSCZWFXQKITHSL-OKCNGXCSSA-N

Clogestone acetate (USANTooltip United States Adopted Name) (developmental code name AY-11440), also known as chlormadinol acetate or as 3β,17α-diacetoxy-6-chloropregna-4,6-diene-20-one,[1] is a steroidal progestin which was investigated as a progestin-only contraceptive and postcoital contraceptive but was never marketed.[2][3][4][5] It is the diacetate ester of clogestone, which, similarly was never marketed.[2] Clogestone acetate produces chlormadinone acetate as an active metabolite.[6]

See also

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References

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