Prinaberel

Prinaberel

Clinical data
ATC code	None
Identifiers
IUPAC name (4Z)-2-Fluoro-4-(5-hydroxy-7-vinyl-1,3-benzoxazol-2(3H)-ylidene)-2,5-cyclohexadien-1-one
CAS Number	524684-52-4
PubChem CID	5326893
ChemSpider	4484184
UNII	A9C8MNF7CA
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C15H10FNO3
Molar mass	271.247 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C3\C=C/C(=C2/Oc1c(cc(O)cc1N2)\C=C)/C=C3/F
InChI InChI=1S/C15H10FNO3/c1-2-8-5-10(18)7-12-14(8)20-15(17-12)9-3-4-13(19)11(16)6-9/h2-7,17-18H,1H2/b15-9- Key:FCXYSEXZEGPLGG-DHDCSXOGSA-N

Prinaberel (INN, USAN) (developmental code names ERB-041, WAY-202041) is a synthetic, nonsteroidal, and highly selective agonist of the ERβ subtype of the estrogen receptor. It is used in scientific research to elucidate the role of the ERβ receptor. Studies have indicated that selective ERβ agonists like prinaberel could be useful in the clinical treatment of a variety of medical conditions including inflammatory bowel disease, rheumatoid arthritis, endometriosis, and sepsis. Accordingly, prinaberel either was or still is under investigation by Wyeth for the treatment of some of these conditions.

See also

• Diarylpropionitrile
• ERB-196
• Erteberel
• WAY-200070
• WAY-214156

External links

• Prinaberel - AdisInsight