Doisynoestrol

Doisynoestrol
Clinical data
Trade names	Fenocyclin, Surestrine, Surestryl
Other names	Diosynestrol; Fenocycline; Fenocyclin; Phenocyclin; RS-2874; Dehydrofolliculinic acid; cis-Bisdehydrodoisynolic acid 7-methyl ether; BDDA ME; NSC-56846; NSC-122041
Routes of; administration	By mouth
Drug class	Nonsteroidal estrogen
Identifiers
	IUPAC name 1-Ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-phenanthrene-2-carboxylic acid;
CAS Number	15372-34-6;
PubChem CID	97911;
ChemSpider	88384;
UNII	2O436BJQ6T;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C19H22O3
Molar mass	298.382 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1C2=C(CCC1(C)C(=O)O)C3=C(C=C2)C=C(C=C3)OC;
	InChI InChI=1S/C19H22O3/c1-4-17-16-7-5-12-11-13(22-3)6-8-14(12)15(16)9-10-19(17,2)18(20)21/h5-8,11,17H,4,9-10H2,1-3H3,(H,20,21); Key:HZZSXUIUESWVSS-UHFFFAOYSA-N;

Doisynoestrol (brand names Fenocyclin, Surestrine, Surestryl; former developmental code name RS-2874), also known as fenocycline, as well as cis-bisdehydrodoisynolic acid 7-methyl ether (BDDA ME), is a synthetic nonsteroidal estrogen of the doisynolic acid group that is no longer marketed.^[1]^[2] It is a methyl ether of bisdehydrodoisynolic acid.^[1] Doisynoestrol was described in the literature in 1945.^[1] It has about 0.02% of the relative binding affinity of estradiol for the estrogen receptor.^[3]

References

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