Neuronal calcium sensor
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Neuronal Calcium Sensor is a large family of proteins which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin, GCAP, neurocalcin, visinin etc.[1] All the members carry 4 EF hand motifs (out of which only 2 or 3 bind calcium) and an N-myristoyl group.[2]
Members of NCS family
[edit | edit source]- Highly evolutionarily conserved [3]
- NCS1 (Frequenin)[4]
- VILIP-1 (Visinin-like-protein-1)
- HPCAL4 (Visinin-like-protein-2)
- HPCAL1 (Visinin-like-protein-3)
- hippocalcin
- neurocalcin
- recoverin
- Guanylate cyclase activator proteins (GCAPs)
- Potassium Channel interacting proteins (KChIPs 1–4), including:
KCNIP1, KCNIP2, Calsenilin or DREAM/KChIP-3/KCNIP3 (downstream regulatory element antagonist modulator/potassium channel interacting protein), KCNIP4
References
[edit | edit source]- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
External links
[edit | edit source]- Neuronal+Calcium-Sensor+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- NCS proteins
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