Disulergine

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Disulergine
File:Disulergine structure.png
Clinical data
Other namesCH-29717; CH 29-717; Sulergine; N,N-Dimethyl-N'-(6-methylergoline-8α-yl)sulfamide
Drug classDopamine agonist; Prolactin inhibitor
Identifiers
  • (6aR,9S,10aR)-9-(dimethylsulfamoylamino)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC17H24N4O2S
Molar mass348.47 g·mol−1
3D model (JSmol)
  • CN1C[C@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)NS(=O)(=O)N(C)C
  • InChI=1S/C17H24N4O2S/c1-20(2)24(22,23)19-12-8-14-13-5-4-6-15-17(13)11(9-18-15)7-16(14)21(3)10-12/h4-6,9,12,14,16,18-19H,7-8,10H2,1-3H3/t12-,14+,16+/m0/s1
  • Key:VUEGYUOUAAVYAS-JGGQBBKZSA-N

Disulergine (INNTooltip International Nonproprietary Name; developmental code names CH-29717 or CH 29-717) is a dopamine agonist of the ergoline family described as a prolactin inhibitor which was never marketed.[1][2][3][4] It is known to be a metabolite of mesulergine.[5][6] The drug was first described in the literature by 1976.[1][3]

See also

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References

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