PCCG-4

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PCCG-4
Identifiers
  • (2S,1'S,2'S,3'R)-2-(2'Carboxy-3'-phenylcyclopropyl)glycine
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
ChEMBL
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC12H13NO4
Molar mass235.239 g·mol−1
3D model (JSmol)
  • C1=CC=C(C=C1)[C@@H]2[C@@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N
  • InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1 checkY
  • Key:IFLWVSHRWAIVQF-KATARQTJSA-N checkY
  (verify)

PCCG-4 is a research drug which acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3), with slight selectivity for mGluR2 although not sufficient to distinguish mGluR2 and mGluR3 responses from each other. It is used in research into the function of the group II metabotropic glutamate receptors.[1][2][3][4][5]

References

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