ACPD
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| Names | |
|---|---|
| Preferred IUPAC name
1-Aminocyclopentane-1,3-dicarboxylic acid[1] | |
| Identifiers | |
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3D model (JSmol)
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| Abbreviations | ACPD |
| ChEMBL | |
| ChemSpider | |
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| MeSH | 1-amino-1,3-dicarboxycyclopentane |
PubChem CID
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| RTECS number |
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CompTox Dashboard (EPA)
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| Properties | |
| C7H11NO4 | |
| Molar mass | 173.168 g·mol−1 |
| Appearance | White crystals |
| 20 g dm−3 | |
| Solubility in ethanol | 240 mg dm−3 |
| log P | −0.709 |
| Acidity (pKa) | 2.112 |
| Basicity (pKb) | 11.885 |
| Isoelectric point | 2.84 |
| Hazards | |
| GHS labelling: | |
| Warning | |
| H302, H312, H315, H319, H332, H335 | |
| P261, P280, P305+P351+P338 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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1-Amino-1,3-dicarboxycyclopentane (ACPD) is a chemical compound that binds to the metabotropic glutamate receptor (mGluR),[2] acting as a mGluR agonist. ACPD is a rigid analogue of the neurotransmitter glutamate and does not activate ionotropic glutamate receptors.[3] However, it has been reported to be an agonist of the glycine site of the NMDA receptor.[citation needed] ACPD can induce convulsions in neonatal rats.[4]
References
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