CECXG

CECXG
	File:CECXG structure.png
Identifiers
	IUPAC name 2-(1'SR,2'SR,3'SR)-2'-carboxy-3'-ethylcyclopropyl-2-(9-xanthylmethyl)glycine;
CAS Number	216164-12-4 ;
PubChem CID	44329042;
ChemSpider	28190823 ;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C22H23NO5
Molar mass	381.428 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c4cccc2c4Oc3ccccc3C2CC(N)(C(O)=O)C1C(C(=O)O)C1CC;
	InChI InChI=1S/C22H23NO5/c1-2-12-18(20(24)25)19(12)22(23,21(26)27)11-15-13-7-3-5-9-16(13)28-17-10-6-4-8-14(15)17/h3-10,12,15,18-19H,2,11,23H2,1H3,(H,24,25)(H,26,27)/t12-,18+,19+,22+/m1/s1 ; Key:NBAKIHCDPVZWRB-KQLBNOIASA-N ;
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CECXG (3'-ethyl-LY-341,495) is a research drug which acts as a potent and selective antagonist for the group II metabotropic glutamate receptors (mGluR_2/3), with reasonable selectivity for mGluR₃. While it is some five times less potent than LY-341,495 at mGluR₃, it has 38x higher affinity for mGluR₃ over mGluR₂,^[1] making it one of the few ligands available that is able to distinguish between these two closely related receptor subtypes.^[2]^[3]^[4]

References

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Identifiers
File:CECXG structure.png
IUPAC name 2-(1'SR,2'SR,3'SR)-2'-carboxy-3'-ethylcyclopropyl-2-(9-xanthylmethyl)glycine
CAS Number	216164-12-4^Y
PubChem CID	44329042
ChemSpider	28190823^N
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₂H₂₃NO₅
Molar mass	381.428 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c4cccc2c4Oc3ccccc3C2CC(N)(C(O)=O)C1C(C(=O)O)C1CC
InChI InChI=1S/C22H23NO5/c1-2-12-18(20(24)25)19(12)22(23,21(26)27)11-15-13-7-3-5-9-16(13)28-17-10-6-4-8-14(15)17/h3-10,12,15,18-19H,2,11,23H2,1H3,(H,24,25)(H,26,27)/t12-,18+,19+,22+/m1/s1^N Key:NBAKIHCDPVZWRB-KQLBNOIASA-N^N
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CECXG

References

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