LSN2463359

LSN2463359

Names
IUPAC name N-Propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide
Identifiers
CAS Number	1401031-52-4 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL2431212
ChemSpider	30835751.html : 30835751
ECHA InfoCard
EC Number	802-759-0
E number
IUPHAR/BPS	6394
PubChem CID	72551298
CompTox Dashboard (EPA)	{{#property:P3117}}
InChI InChI=1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20) Key: STAFRSGTRKNXHF-UHFFFAOYSA-N
SMILES CC(C)NC(=O)C1=NC=C(C=C1)C#CC2=CC=NC=C2
Properties
Chemical formula	C16H15N3O
Molar mass	265.316 g·mol−1
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H319, H335
Precautionary statements	P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

LSN2463359 is a drug used in scientific research.

Mechanism of action

LSN2463359 is a positive allosteric modulator of the mGluR₅, which means it increases the activity of glutamate (an excitatory neurotransmitter) at this receptor.

Potential uses

A study has found that LSN2463359 and similar drugs can be used as a treatment to some aspects of cognitive deficits in schizophrenia. Another study also mention that it could be used in the treatment of schizophrenia due to the potential interactions between NMDA receptors and mGluR₅.