Glycine receptor, alpha 1
(Redirected from GLRA1)
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Glycine receptor subunit alpha-1 is a protein that in humans is encoded by the GLRA1 gene.[1][2]
Function
[edit | edit source]The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed solely of alpha subunits. The GLRB gene encodes the alpha subunit of the receptor.[3]
Clinical significance
[edit | edit source]Mutations in the gene have been associated with hyperekplexia, a neurologic syndrome associated with an exaggerated startle reaction.[4][5]
See also
[edit | edit source]References
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Further reading
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External links
[edit | edit source]- Overview of all the structural information available in the PDB for UniProt: P23415 (Glycine receptor subunit alpha-1) at the PDBe-KB.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
