CB-86

CB-86

Identifiers
IUPAC name N-cyclopropyl-8-[3-hydroxy-5-(2-methyloctan-2-yl)phenoxy]octanamide
CAS Number	1150586-64-3
PubChem CID	42625202
ChemSpider	24705451
ChEMBL	ChEMBL490648
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C26H43NO3
Molar mass	417.634 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCCC(C)(C)C1=CC(=CC(=C1)OCCCCCCCC(=O)NC2CC2)O
InChI InChI=1S/C26H43NO3/c1-4-5-6-11-16-26(2,3)21-18-23(28)20-24(19-21)30-17-12-9-7-8-10-13-25(29)27-22-14-15-22/h18-20,22,28H,4-17H2,1-3H3,(H,27,29) Key:PVAOGZXUOOHSMN-UHFFFAOYSA-N

CB-86 is a synthetic cannabinoid drug which was developed as a hybrid between classical/nonclassical cannabinoids such as THC and CP 47,497 with endogenous cannabinoid ligands such as anandamide. It acts as a partial agonist at CB1 receptors with a K_i of 5.6 nM, and an antagonist of CB2 receptors with a K_i of 7.9 nM. It has analgesic effects in studies on mice.

See also

• CB-13
• O-1812
• O-1871