AM-905

AM-905
	File:AM-905.svg
Identifiers
	IUPAC name (6aR,9R,10aR)-3-[(E)-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol;
CAS Number	181139-62-8 check;
PubChem CID	9998522;
ChemSpider	8174103 check;
UNII	TJ6JD73J07;
ChEMBL	ChEMBL127848 check;
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).;
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C23H34O3
Molar mass	358.522 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCC/C=C/c(cc1O)cc(OC(C)(C)C2CC3)c1C2CC3CO;
	InChI InChI=1S/C23H34O3/c1-4-5-6-7-8-9-16-13-20(25)22-18-12-17(15-24)10-11-19(18)23(2,3)26-21(22)14-16/h8-9,13-14,17-19,24-25H,4-7,10-12,15H2,1-3H3/b9-8+/t17-,18-,19-/m1/s1 check; Key:NJIKRWBGUIYKJM-OKMMTOMJSA-N check;
	(verify)

AM-905 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is conformationally restricted by virtue of the double bond on its side chain, leading an increased affinity for and selectivity between CB₁ and CB₂ receptors.^[1] It is a potent and reasonably selective agonist for the CB₁ cannabinoid receptor, with a K_i of 1.2 nM at CB₁ and 5.3 nM at CB₂.^[2]

References

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[1]

[2]

AM-905

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Identifiers
File:AM-905.svg
IUPAC name (6aR,9R,10aR)-3-[(E)-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
CAS Number	181139-62-8^checkY
PubChem CID	9998522
ChemSpider	8174103^checkY
UNII	TJ6JD73J07
ChEMBL	ChEMBL127848^checkY
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₃H₃₄O₃
Molar mass	358.522 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCCCC/C=C/c(cc1O)cc(OC(C)(C)C2CC3)c1C2CC3CO
InChI InChI=1S/C23H34O3/c1-4-5-6-7-8-9-16-13-20(25)22-18-12-17(15-24)10-11-19(18)23(2,3)26-21(22)14-16/h8-9,13-14,17-19,24-25H,4-7,10-12,15H2,1-3H3/b9-8+/t17-,18-,19-/m1/s1^checkY Key:NJIKRWBGUIYKJM-OKMMTOMJSA-N^checkY
(verify)

AM-905

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