Etodesnitazene

Desnitroetonitazene

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Legal status
Legal status	BR: Class F1 (Prohibited narcotics) DE: Anlage II (Authorized trade only, not prescriptible) UK: Class A US: Schedule I
Identifiers
IUPAC name 2-[2-[(4-Ethoxyphenyl)methyl]benzimidazol-1-yl]-N,N-diethylethanamine
CAS Number	14030-76-3 checkY
PubChem CID	149797386
ChemSpider	128909207
UNII	H7YW5L26CS
KEGG	C22827
ChEBI	CHEBI:234368
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H29N3O
Molar mass	351.494 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCN1C2=CC=CC=C2N=C1CC3=CC=C(C=C3)OCC
InChI InChI=1S/C22H29N3O/c1-4-24(5-2)15-16-25-21-10-8-7-9-20(21)23-22(25)17-18-11-13-19(14-12-18)26-6-3/h7-14H,4-6,15-17H2,1-3H3 Key:BMLPNUNXHUGDOI-UHFFFAOYSA-N

Etodesnitazene (also known as desnitroetonitazene, etazen, etazene, and etazone) is a benzimidazole-derived opioid analgesic drug, which was originally developed in the late 1950s alongside etonitazene and a range of related derivatives. It is many times less potent than etonitazene itself, but still 70 times more potent than morphine in animal studies. Corresponding analogues where the N,N-diethyl group is replaced by piperidine or pyrrolidine rings also retain significant activity (10 times and 20 times morphine, respectively). Etodesnitazene has been sold as a designer drug, first being identified in both Poland and Finland in March 2020.

Legal Status

United Kingdom

Since 15 January 2025 it is covered by the UK's generic definition on 2-benzyl benzimidazole derived opioids because it contains the 2-(2-benzyl-benzimidazol-1-yl)ethanamine backbone with only the following modification:

• The phenyl ring of the benzyl system is substituted by an alkoxy group containing two carbon atoms.

See also

• Brorphine
• Etonitazepyne
• Etoacetazene
• Etocyanazene
• Etomethazene
• Isotonitazene
• Metonitazene
• Metodesnitazene
• Protodesnitazene
• MCHB-1
• List of benzimidazole opioids