Butaxamine

Butaxamine
Clinical data
Other names	Butoxamine
ATC code	None;
Identifiers
	IUPAC name (1S,2S)-1-(2,5-Dimethoxyphenyl)-2-(tert-butylamino)propan-1-ol;
CAS Number	1937-89-9 ;
PubChem CID	134495;
ChemSpider	118552 ;
UNII	0NM31M53PW;
ChEMBL	ChEMBL289093;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C15H25NO3
Molar mass	267.369 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H]([C@@H](C1=C(C=CC(=C1)OC)OC)O)NC(C)(C)C;
	InChI InChI=1S/C15H25NO3/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6/h7-10,14,16-17H,1-6H3/t10-,14-/m0/s1; Key:TWUSDDMONZULSC-HZMBPMFUSA-N;
	(verify)

Butaxamine (INN; also known as butoxamine) is a β₂-selective beta blocker.^[1]^[2] Its primary use is in experimental situations in which blockade of β₂ receptors is necessary to determine the activity of the drug (i.e. if the β₂ receptor is completely blocked, but the given effect is still present, the given effect is not a characteristic of the β₂ receptor). It has no clinical use. An alternative name is α-(1-[tert-butylamino]ethyl)-2,5-dimethoxybenzyl alcohol.

References

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[1]

[2]

v t e Beta blockers (C07)
β, non-selective	Alprenolol Bopindolol Bupranolol Carteolol Cloranolol Mepindolol Nadolol Oxprenolol Penbutolol Pindolol/Iodopindolol Propranolol^# Sotalol Tertatolol Timolol^#
β₁-selective	Acebutolol Atenolol Betaxolol Bevantolol Bisoprolol^# Celiprolol Epanolol Esmolol Landiolol Metoprolol Nebivolol Practolol Talinolol
β₂-selective	Butaxamine
α₁- + β-selective	Arotinolol Carvedilol Labetalol
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Butaxamine

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Butaxamine

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