AFDX-384

AFDX-384
Identifiers
	IUPAC name N-(2-[(2R)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl)-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide;
CAS Number	118290-27-0 ;
PubChem CID	119357;
ChemSpider	26233613 ;
ChEBI	CHEBI:73338 ;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C27H38N6O2
Molar mass	478.641 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1Nc2cccnc2N(c4c1cccc4)C(=O)NCCN3CCCCC3CN(CCC)CCC;
	InChI InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)/t21-/m1/s1 ; Key:MZDYABXXPZNUCT-OAQYLSRUSA-N ;
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AFDX-384 (BIBN-161) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors, with selectivity for the M₂ and M₄ subtypes. It is used mainly for mapping the distribution of M₂ and M₄ muscarinic receptors in the brain, and studying their involvement in the development and treatment of dementia and schizophrenia.^[1]^[2]^[3]^[4]^[5]^[6]^[7]

References

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AFDX-384

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References

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Identifiers

IUPAC name N-(2-[(2R)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl)-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
CAS Number	118290-27-0^Y
PubChem CID	119357
ChemSpider	26233613^Y
ChEBI	CHEBI:73338^N
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₇H₃₈N₆O₂
Molar mass	478.641 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C1Nc2cccnc2N(c4c1cccc4)C(=O)NCCN3CCCCC3CN(CCC)CCC
InChI InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)/t21-/m1/s1^Y Key:MZDYABXXPZNUCT-OAQYLSRUSA-N^Y
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AFDX-384

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References

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