Meprin B
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Meprin B (EC 3.4.24.63, meprin-b) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
- Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of -His5-Leu-, -Leu6-Cys-, -Ala14-Leu- and -Cys19-Gly- bonds in insulin B chain
Even though it is primarily found and embedded into the cell membrane it can also be found in the extracellular space.[5] Like other meprins it can hydrolyze different molecules.[5]
This membrane-bound metalloendopeptidase is present in mouse intestines.
References
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External links
[edit | edit source]- Meprin+B at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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