ADAM33
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene.[1][2]
Function
[edit | edit source]This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness.[3] Alternative splicing of this gene results in two transcript variants encoding different isoforms.[2]
References
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Further reading
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External links
[edit | edit source]- The MEROPS online database for peptidases and their inhibitors: M12.244
- Human ADAM33 genome location and ADAM33 gene details page in the UCSC Genome Browser.
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