Macrophage elastase
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| Macrophage elastase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.24.65 | ||||||||
| CAS no. | 2594837 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Macrophage elastase (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
- Hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at -Ala14-Leu- and -Tyr16-Leu- in the B chain of insulin
This enzyme belongs to the peptidase family M10.
See also
[edit | edit source]References
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External links
[edit | edit source]- Macrophage+elastase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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