CD6
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene.[1][2]
Function
[edit | edit source]This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation.[1]
Clinical significance
[edit | edit source]Certain alleles of this gene may be associated with susceptibility to multiple sclerosis.[3][4]
See also
[edit | edit source]References
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Further reading
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External links
[edit | edit source]- CD6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Human CD6 genome location and CD6 gene details page in the UCSC Genome Browser.
- Overview of all the structural information available in the PDB for UniProt: P30203 (Human T-cell differentiation antigen CD6) at the PDBe-KB.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
