Acotiamide
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| Clinical data | |
|---|---|
| Trade names | Acofide, others |
| Other names | YM-443, Z-338 |
| Routes of administration | By mouth |
| ATC code | |
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| Pharmacokinetic data | |
| Protein binding | 84.21–85.95% |
| Metabolism | UGT1A8 and 1A9 (major) |
| Elimination half-life | 10.9–21.7 hours |
| Excretion | Feces (92.7%), urine (5.3%)[1] |
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| E number | {{#property:P628}} |
| CompTox Dashboard (EPA) |
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| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C21H30N4O5S |
| Molar mass | 450.55 g·mol−1 |
| 3D model (JSmol) | |
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  (what is this?) (verify) | |
Acotiamide, sold under the brand names Acofide,[2][3] and Dyspevict is a medication manufactured and approved in Japan and Russia[4] for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.[5] It acts as an acetylcholinesterase inhibitor.
References
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