ASF1B
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Histone chaperone ASF1B is a protein that in humans is encoded by the ASF1B gene.[1][2][3]
Function
[edit | edit source]This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.[3]
Interactions
[edit | edit source]ASF1B has been shown to interact with TLK2,[2][4] CHAF1B,[1][4] TLK1[2][4] and CHAF1A.[1][4]
References
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Further reading
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External links
[edit | edit source]- Human ASF1B genome location and ASF1B gene details page in the UCSC Genome Browser.
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