ORG-25435

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ORG-25435
File:ORG-25435 Structure.svg
Identifiers
  • (2,6-dimethoxy-4-methylphenyl)-(2R)-2-[bis(2-methoxyethyl)amino]butanoate
CAS Number
PubChem CID
UNII
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC19H31NO6
Molar mass369.458 g·mol−1
3D model (JSmol)
  • COc1cc(C)cc(OC)c1OC(=O)C(CC)N(CCOC)CCOC

ORG-25435 is a synthetic drug developed by Organon International, which acts as a GABAA receptor positive allosteric modulator, and produces sedative effects. It has been researched for use as an intravenous anesthetic agent, with positive results in initial trials, although negative side effects like hypotension and tachycardia, as well as unpredictable pharmacokinetics at higher doses, have meant it has ultimately not been adopted for medical use.[1][2]

References

[edit | edit source]
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