FUT4

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fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Identifiers
SymbolFUT4
Alt. symbolsCD15, FCT3A, ELFT, SSEA-1, LeX
NCBI gene2526
HGNC4015
OMIM104230
RefSeqNM_002033
UniProtP22083
Other data
EC number2.4.1.152
LocusChr. 11 q21
Search for
StructuresSwiss-model
DomainsInterPro

Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), also known as FUT4, is an enzyme which in humans is encoded by the FUT4 gene.[1][2][3]

Function

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The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).[4][5]

References

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.