CYP305M2 (formerly called LM16181) is a cytochrome P450 enzyme found in migratory locust (Locusta migratoria) that catalyzes the key step of biosynthesis of phenylacetonitrile (PAN).[1][2] PAN in turn is used as an aposematic chemical defense against predators.
Biosynthesis of phenylacetonitrile catalyzed by CYP305M2 and subsequent decomposition to benzaldehyde and cyanide
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| CYP1 | |
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| CYP2 | |
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| CYP3 (CYP3A) | |
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| CYP4 | |
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| CYP5-20 | |
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| CYP21-49 | |
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| CYP51-69 | |
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| CYP71-99 |
- CYP71 (C1, C2, C3, C4, Z6, AJ4, AV1, BA1)
- CYP72A1
- CYP73A1
- CYP74 (D1)
- CYP75 (A1, B1)
- CYP76 (B6, M7)
- CYP79 (A1, A2, B1, B2, B3, D1, D2, D3, D4)
- CYP80 (A1, B1, G2)
- CYP81 (E1, E3, E7, E9)
- CYP88D6
- CYP90C1
- CYP93E1
- CYP97C1
- CYP99A3
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| CYP101-281 | |
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| CYP301-499 | |
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| CYP501-699 | |
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| CYP701-999 | |
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