CLCA1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.[1][2]
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.[2] Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease.[3]
See also
[edit | edit source]References
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Further reading
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External links
[edit | edit source]- CLCA1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Human CLCA1 genome location and CLCA1 gene details page in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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