CKAP5
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene.[1][2][3] It is the homolog of the Xenopus protein XMAP215[4] and is also known as ch-Tog.
It has at least two distinct roles in spindle formation: it protects kinetochore microtubules from depolymerization by MCAK (KIF2C), and ch-Tog plays an essential role in centrosomal microtubule assembly, a function independent of MCAK activity.[5]
Interactions
[edit | edit source]CKAP5 has been shown to interact with TACC1.[6][7]
References
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External links
[edit | edit source]- Human CKAP5 genome location and CKAP5 gene details page in the UCSC Genome Browser.
Further reading
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