CDC5L
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Cell division cycle 5-like protein is a protein that in humans is encoded by the CDC5L gene.[1][2][3]
Function
[edit | edit source]The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.[3]
Interactions
[edit | edit source]CDC5L has been shown to interact with:
- ASF/SF2,[4]
- BZW1,[4]
- CWC15,[4]
- DNA-PKcs,[4]
- DYNC1H1,[4]
- GCN1L1,[4]
- HSPA8,[4]
- ILF2,[4]
- PLRG1,[4][5][6][7]
- PPM1D,[4]
- PPP1CA,[4]
- PRPF19,[4]
- RBMX[4] and
- RPL12,[4]
- RPL13,[4]
- RPS16,[4]
- RPS25,[4]
- SF3A1,[4]
- SF3B1,[4]
- SF3B2,[4]
- SF3B4,[4]
- SFPQ,[4]
- SRSF2,[4]
- SNRPA1,[4]
- SNRPD3,[4]
- SRRM1,[4]
- Small nuclear ribonucleoprotein D1,[4]
- Small nuclear ribonucleoprotein D2,[4]
- Small nuclear ribonucleoprotein polypeptide A,[4]
- TOP2A,[4] and
- TTF2.[8]
See also
[edit | edit source]References
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Further reading
[edit | edit source]- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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External links
[edit | edit source]- Human CDC5L genome location and CDC5L gene details page in the UCSC Genome Browser.
