Pinaverium bromide

Pinaverium bromide
Clinical data
ATC code	A03AX04 (WHO) ;
Identifiers
	IUPAC name 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium bromide;
CAS Number	53251-94-8 check;
PubChem CID	40703;
DrugBank	DBSALT001130 check;
ChemSpider	37181 ☒;
UNII	7SCF54H12J;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C26H41Br2NO4
Molar mass	591.425 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)Cc4cc(c(cc4Br)OC)OC)C.[Br-];
	InChI InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1 ☒; Key:IKGXLCMLVINENI-UHFFFAOYSA-M ☒;
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Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.^[1]

Pinaverium bromide was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and marketed globally using the brand names Dicetel and Eldicet. Generic pinaverium is available in South Korea under a trade name of Disten^[2] and in Argentina as Nulite.^[3]

Indications

It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) including abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.^[4]

References

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Clinical data

ATC code	A03AX04 (WHO)
Identifiers
IUPAC name 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium bromide
CAS Number	53251-94-8^checkY
PubChem CID	40703
DrugBank	DBSALT001130^checkY
ChemSpider	37181^☒N
UNII	7SCF54H12J
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₆H₄₁Br₂NO₄
Molar mass	591.425 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)Cc4cc(c(cc4Br)OC)OC)C.[Br-]
InChI InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1^☒N Key:IKGXLCMLVINENI-UHFFFAOYSA-M^☒N
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Pinaverium bromide

Indications

References

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