Vibralactone
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Vibralactones are a group of related terpenoid chemical compounds, the first of which were isolated from the Basidiomycete Boreostereum vibrans in 2006.[1] Additional vibralactones have also been isolated from the fungus Stereum hirsutum.[2]
Vibralactone A has attracted research interest because it is an inhibitor of pancreatic lipase (IC50 0.4 μg/mL) with in vitro activity comparable to that of the obesity drug orlistat.[1][3]
Several laboratory syntheses of vibralactone A have been developed.[3][4]
Chemical structures
[edit | edit source]Vibralactone A | Vibralactone B | Vibralactone C |
Vibralactone D | Vibralactone E | Vibralactone F |
References
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