Valencene synthase

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Valencene synthase
Identifiers
EC no.4.2.3.73
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Valencene synthase (EC 4.2.3.73) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming).[1] It is a terpene cyclase enzyme responsible for the biosynthesis of valencene, a sesquiterpene, using farnesyl pyrophosphate as its substrate. The first such enzyme was isolated using orange cDNA.[2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-valencene + diphosphate

The recombinant enzyme from Vitis vinifera forms (+)-valencene and (-)-7-epi-α-selinene.

References

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