VPS11
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the VPS11 gene.[1]
Function
[edit | edit source]Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.[1]
Interactions
[edit | edit source]VPS11 has been shown to interact with VPS18,[2] VPS33A[2] and STX7.[2]
References
[edit | edit source]Further reading
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