Usona Institute

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Usona Institute
Company type501(c)(3) non-profit medical research organization
IndustryPharmaceutical; Psychedelic medicine
Founded2014; 12 years ago (2014) in Madison, Wisconsin, United States
FounderBill Linton; Malynn Utzinger[1]
Headquarters,
Number of employees
18[1] (March 2019[1])
Websitewww.usonainstitute.org

The Usona Institute is a 501(c)(3) non-profit medical research organization (MRO) which is developing psychedelic drugs for potential medical use.[2][1] It was launched by scientist and entrepreneur Bill Linton, who is the founder of the biotechnology company Promega Corporation, and by physician Malynn Utzinger in 2014.[2][1]

The organization is developing psilocybin (4-HO-DMT) for treatment of depression.[3][4] It started a phase 2 clinical trial of psilocybin for major depressive disorder in 2019.[2] The same year, this candidate received Food and Drug Administration (FDA) "breakthrough therapy" designation.[2][5] This clinical trial has since been completed and its psilocybin candidate is now in phase 3 clinical studies.[6][7] In July 2024, it was said that the Usona Institute was leading the largest clinical trial of ongoing psilocybin treatment for depression, a phase 3 trial with 240 participants treated with 5 or 25 mg psilocybin or placebo.[8] Other candidates of the institute include mebufotenin (5-MeO-DMT)[9] and bufotenin (5-HO-DMT),[10] among others.[11][12]

The Usona Institute is notable in manufacturing large quantities of synthetic psilocybin and supplying the drug for clinical trials throughout the world, which it does for free for research purposes.[2][13]

See also

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References

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