Unidimensional Fatigue Impact Scale

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The Unidimensional Fatigue Impact Scale (U-FIS) is a disease-specific patient-reported outcome measure which measures the impact of multiple sclerosis related fatigue.[1] It is a 22-item unidimensional scale which is based on needs-based quality of life theory.[1]

Background

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The U-FIS was developed by Galen Research and published in 2009.[1] It was derived from the Fatigue Impact Scale, a scale identified by the Multiple Sclerosis Council for Clinical Practice Guidelines “as the most appropriate for assessing the impact of MS-related fatigue on quality of life”.[2]

Data from the FIS went through Rasch analysis and additional items were added from interviews with multiple sclerosis patients. The U-FIS was then tested for validity via patient interviews and a validation survey.[1]

International Use

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The U-FIS has been translated and validated into eight different language versions: Canadian English, Canadian French, German, Swedish, Italian, French, US English and Spanish.[3]

It has been recommended for use in determining fatigue impact by an independent meta analysis[4] and has also been utilized in a study investigating the role of neuroticism, perfectionism and depression in chronic fatigue syndrome.[5]

References

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