Ueli Aebi

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Ueli Aebi
Ueli Aebi (2012)
Born(1946-05-31)31 May 1946
Bern, Switzerland
Died28 November 2025(2025-11-28) (aged 79)
CitizenshipSwiss
Known forIntegrative structural biology
Scientific career
FieldsStructural Biology
InstitutionsUniversity of Bern, Maurice E. Müller Institute for Structural Biology, University of Basel

Ueli Aebi (31 May 1946 – 28 November 2025) was a Swiss structural biologist and co-founder[1] of the Maurice E. Müller Institute for Structural Biology at the Biozentrum University of Basel.

Background

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Aebi studied physics, mathematics, and molecular biology at the Universities of Bern and Basel from 1967 to 1974, graduating in 1977 in biophysics at the University of Basel. After establishing his academic career in the United States (University of California, Los Angeles, Johns Hopkins University School of Medicine), in 1986 he returned to the Biozentrum as professor of structural biology. He was co-founder of the Maurice E. Müller Institute for Structural Biology and its director from 1986 until reaching emeritus status in 2011.[2][3] Aebi died on 28 November 2025, at the age of 79.[4]

Aebi is recognised as a pioneer in integrative structural biology as well as mechano- and nanobiology.[5][6] His work focused on the elucidation of the structure, function and assembly of the cyto- and nucleoskeleton and the nuclear pore complex (NPC), as well as the amyloid fibrils that are a hallmark of Alzheimer's disease.[7] He studied the architecture of diverse supramolecular assemblies using a combination of light, electron and atomic force microscopy, X-ray crystallography, and protein engineering.[8] Among others, Aebi determined the 3-dimensional structure of the NPC by cryo-electron tomography.[9]

Awards and honors

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References

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  10. ^ Biozentrum University of Basel: Charles University in Prague awards Prof. Ueli Aebi an honorary doctorate Archived 2013-10-29 at the Wayback Machine
  11. ^ Two prestigious awards for Ueli Aebi Archived 2016-03-04 at the Wayback Machine
  12. ^ Biozentrum University of Basel: Two prestigious awards for Ueli Aebi Archived 2013-10-29 at the Wayback Machine
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