USF2
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene.[1][2]
Function
[edit | edit source]This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through Pyridine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.[2]
Interactions
[edit | edit source]USF2 has been shown to interact with USF1 (human gene),[3][4] PPRC1[5] and BRCA1.[6]
Regulation
[edit | edit source]The USF2 gene is repressed by the microRNA miR-10a.[7]
References
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Further reading
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External links
[edit | edit source]
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