UBE4A
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Ubiquitin conjugation factor E4 A is a protein that in humans is encoded by the UBE4A gene.[1][2]
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.[2]
References
[edit | edit source]Further reading
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