TrkB IRES
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| TrkB IRES | |
|---|---|
| File:RF00547.jpg Predicted secondary structure and sequence conservation of IRES_TrkB | |
| Identifiers | |
| Symbol | IRES_TrkB |
| Rfam | RF00547 |
| Other data | |
| RNA type | Cis-reg; IRES |
| Domain | Eukaryota |
| GO | GO:0043022 |
| SO | SO:0000243 |
| PDB structures | PDBe |
The TrkB internal ribosome entry site (IRES) is an RNA element which is present in the 5' UTR sequence of the mRNA. TrkB is a neurotrophin receptor which is essential for the development and maintenance of the nervous system. The internal ribosome entry site IRES element allows cap-independent translation of TrkB which may be needed for efficient translation in neuronal dendrites.[1]
See also
[edit | edit source]References
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